5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline → HCID 67358873, compound

HRID 1668625Notes

Reaction equation

HRID 1668625 reaction equation
FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.[N:15]1([C:21]2[O:22][C:23]3[C:33]([N:34]=2)=[CH:32][C:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31][C:25]=2[CH:24]=3)[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1.[Cl:35][CH2:36][CH2:37][CH2:38][S:39][C:40]1[N:41]([CH3:56])[C:42]([C:45]2[CH:54]=[CH:53][CH:52]=[C:51]3[C:46]=2[CH:47]=[CH:48][C:49]([CH3:55])=[N:50]3)=[N:43][N:44]=1>>[ClH:35].[ClH:35].[CH3:56][N:41]1[C:42]([C:45]2[CH:54]=[CH:53][CH:52]=[C:51]3[C:46]=2[CH:47]=[CH:48][C:49]([CH3:55])=[N:50]3)=[N:43][N:44]=[C:40]1[S:39][CH2:38][CH2:37][CH2:36][N:29]1[CH2:28][CH2:27][C:26]2[CH:32]=[C:33]3[N:34]=[C:21]([N:15]4[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]4)[O:22][C:23]3=[CH:24][C:25]=2[CH2:31][CH2:30]1

Participants

3

Reactant 2

HCID 251050505-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinolineHCID 86638057HCID 86638057, compound

Product 1

HCID 67358873HCID 67358873, compound

Procedure

The title compound was prepared in analogy to General Procedure 1 from 2-(1-piperidinyl)-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine bis(trifluoroacetate) (0.130 mmol) and 5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline and was obtained as a white slightly hygroscopic solid (6.2 μmol).

Sources & evidence

ORD record
ord-d0492ab8b08b4cf39e22490d97a32615
Source dataset
uspto-grants-2011_08
Patent number
US07989444B2

Reaction notes

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