5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline → HCID 67358767, compound

HRID 1668627Notes

Reaction equation

HRID 1668627 reaction equation
[CH3:1][C:2]1[S:3][C:4]2[C:14]([N:15]=1)=[CH:13][C:7]1[CH2:8][CH2:9][NH:10][CH2:11][CH2:12][C:6]=1[CH:5]=2.[Cl:16][CH2:17][CH2:18][CH2:19][S:20][C:21]1[N:22]([CH3:37])[C:23]([C:26]2[CH:35]=[CH:34][CH:33]=[C:32]3[C:27]=2[CH:28]=[CH:29][C:30]([CH3:36])=[N:31]3)=[N:24][N:25]=1>>[ClH:16].[CH3:1][C:2]1[S:3][C:4]2[C:14]([N:15]=1)=[CH:13][C:7]1[CH2:8][CH2:9][N:10]([CH2:17][CH2:18][CH2:19][S:20][C:21]3[N:22]([CH3:37])[C:23]([C:26]4[CH:35]=[CH:34][CH:33]=[C:32]5[C:27]=4[CH:28]=[CH:29][C:30]([CH3:36])=[N:31]5)=[N:24][N:25]=3)[CH2:11][CH2:12][C:6]=1[CH:5]=2

Participants

3

Reactant 2

HCID 251050505-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinolineHCID 59150528HCID 59150528, compound

Product 1

HCID 67358767HCID 67358767, compound

Procedure

The title compound was prepared in analogy to General Procedure 1 from 2-methyl-6,7,8,9-tetrahydro-5H-[1,3]thiazolo[4,5-h][3]benzazepine (0.13 mmol) and 5-{5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline (0.16 mmol) and was obtained as a colourless slightly hygroscopic solid (24 mg).

Sources & evidence

ORD record
ord-6c5acbeb5c6046198122aa8c0310d58d
Source dataset
uspto-grants-2011_08
Patent number
US07989444B2

Reaction notes

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