3-[(3-Chloropropyl)thio]-4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazole → HCID 67364240, compound

HRID 1668628Notes

Reaction equation

HRID 1668628 reaction equation
[CH3:1][C:2]1[S:3][C:4]2[C:14]([N:15]=1)=[CH:13][C:7]1[CH2:8][CH2:9][NH:10][CH2:11][CH2:12][C:6]=1[CH:5]=2.[Cl:16][CH2:17][CH2:18][CH2:19][S:20][C:21]1[N:25]([CH3:26])[C:24]([C:27]2[O:31][CH:30]=[N:29][C:28]=2[CH3:32])=[N:23][N:22]=1>>[ClH:16].[CH3:1][C:2]1[S:3][C:4]2[C:14]([N:15]=1)=[CH:13][C:7]1[CH2:8][CH2:9][N:10]([CH2:17][CH2:18][CH2:19][S:20][C:21]3[N:25]([CH3:26])[C:24]([C:27]4[O:31][CH:30]=[N:29][C:28]=4[CH3:32])=[N:23][N:22]=3)[CH2:11][CH2:12][C:6]=1[CH:5]=2

Participants

3

Reactant 2

HCID 446279943-[(3-Chloropropyl)thio]-4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazoleHCID 59150528HCID 59150528, compound

Product 1

HCID 67364240HCID 67364240, compound

Procedure

The title compound was prepared in analogy to General Procedure 1 from 2-methyl-6,7,8,9-tetrahydro-5H-[1,3]thiazolo[4,5-h][3]benzazepine (0.15 mmol) and 3-[(3-chloropropyl)thio]-4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazole (0.18 mmol) and was obtained as a colourless slightly hygroscopic solid (24 mg).

Sources & evidence

ORD record
ord-d59528c4d37b42fe9b0b04d18157369c
Source dataset
uspto-grants-2011_08
Patent number
US07989444B2

Reaction notes

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