HRID1668633

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID59150509

未命名化合物

HCID59150520

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc2c(-c3nnc(SCCCCN4CCc5cc6nc(C)oc6c(Br)c5CC4)n3C)cccc2n1.Cl

HCID67358502

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to General Procedure 1 from 10-bromo-2-methyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine (100 mg) and 5-{5-[(4-chlorobutyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline (177 mg) and was obtained as a colourless slightly hygroscopic solid (127 mg).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ab14b3da434a4a86bf1dca4d9e7de1dc
来源数据集: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07989444B2
来源说明: uspto-grants-2011_08

反应 SMILES

[Br:1][C:2]1[C:12]2[CH2:11][CH2:10][NH:9][CH2:8][CH2:7][C:6]=2[CH:5]=[C:4]2[N:13]=[C:14]([CH3:16])[O:15][C:3]=12.[Cl:17][CH2:18][CH2:19][CH2:20][CH2:21][S:22][C:23]1[N:24]([CH3:39])[C:25]([C:28]2[CH:37]=[CH:36][CH:35]=[C:34]3[C:29]=2[CH:30]=[CH:31][C:32]([CH3:38])=[N:33]3)=[N:26][N:27]=1>>[ClH:17].[Br:1][C:2]1[C:12]2[CH2:11][CH2:10][N:9]([CH2:18][CH2:19][CH2:20][CH2:21][S:22][C:23]3[N:24]([CH3:39])[C:25]([C:28]4[CH:37]=[CH:36][CH:35]=[C:34]5[C:29]=4[CH:30]=[CH:31][C:32]([CH3:38])=[N:33]5)=[N:26][N:27]=3)[CH2:8][CH2:7][C:6]=2[CH:5]=[C:4]2[N:13]=[C:14]([CH3:16])[O:15][C:3]=12