HRID1668634

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID59150505

未命名化合物

HCID59150509

未命名化合物

PRODUCTS

生成物

结构：CCc1nc2cc3c(c(Br)c2o1)CCN(CCCCSc1nnc(-c2cccc4nc(C)ccc24)n1C)CC3.Cl

HCID67357742

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to General Procedure 1 from 10-bromo-2-ethyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine (105 mg) and 5-{5-[(4-chlorobutyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline (177 mg) and was obtained as a colourless slightly hygroscopic solid (115 mg).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fd2f227209154525a98ad7c8171321e9
来源数据集: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07989444B2
来源说明: uspto-grants-2011_08

反应 SMILES

[Br:1][C:2]1[C:12]2[CH2:11][CH2:10][NH:9][CH2:8][CH2:7][C:6]=2[CH:5]=[C:4]2[N:13]=[C:14]([CH2:16][CH3:17])[O:15][C:3]=12.[Cl:18][CH2:19][CH2:20][CH2:21][CH2:22][S:23][C:24]1[N:25]([CH3:40])[C:26]([C:29]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:30]=2[CH:31]=[CH:32][C:33]([CH3:39])=[N:34]3)=[N:27][N:28]=1>>[ClH:18].[Br:1][C:2]1[C:12]2[CH2:11][CH2:10][N:9]([CH2:19][CH2:20][CH2:21][CH2:22][S:23][C:24]3[N:25]([CH3:40])[C:26]([C:29]4[CH:38]=[CH:37][CH:36]=[C:35]5[C:30]=4[CH:31]=[CH:32][C:33]([CH3:39])=[N:34]5)=[N:27][N:28]=3)[CH2:8][CH2:7][C:6]=2[CH:5]=[C:4]2[N:13]=[C:14]([CH2:16][CH3:17])[O:15][C:3]=12