HRID1668644

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID59150504

未命名化合物

HCID59150509

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc2c(-c3nnc(SCCCCN4CCc5cc6c(cc5CC4)C(=O)N(C(C)C)C6)n3C)cccc2n1.Cl

HCID67358048

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to General Procedure 1 from 2-(1-methylethyl)-3,5,6,7,8,9-hexahydroazepino[4,5-f]isoindol-1(2H)-one (80 mg) and 5-{5-[(4-chlorobutyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline (135 mg) and was obtained as a colourless slightly hygroscopic solid (90 mg).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6a44345ee3174d41b7a3e39b97190a39
来源数据集: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07989444B2
来源说明: uspto-grants-2011_08

反应 SMILES

[CH3:1][CH:2]([N:4]1[C:12](=[O:13])[C:11]2[CH:10]=[C:9]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18][C:8]3=[CH:7][C:6]=2[CH2:5]1)[CH3:3].[Cl:19][CH2:20][CH2:21][CH2:22][CH2:23][S:24][C:25]1[N:26]([CH3:41])[C:27]([C:30]2[CH:39]=[CH:38][CH:37]=[C:36]3[C:31]=2[CH:32]=[CH:33][C:34]([CH3:40])=[N:35]3)=[N:28][N:29]=1>>[ClH:19].[CH3:3][CH:2]([N:4]1[C:12](=[O:13])[C:11]2[CH:10]=[C:9]3[CH2:14][CH2:15][N:16]([CH2:20][CH2:21][CH2:22][CH2:23][S:24][C:25]4[N:26]([CH3:41])[C:27]([C:30]5[CH:39]=[CH:38][CH:37]=[C:36]6[C:31]=5[CH:32]=[CH:33][C:34]([CH3:40])=[N:35]6)=[N:28][N:29]=4)[CH2:17][CH2:18][C:8]3=[CH:7][C:6]=2[CH2:5]1)[CH3:1]