Methanamine, N-methoxy-, hydrochloride (1:1) → HCID 57825237, compound

Participants

Reaction Steps

In analogy to the procedure described for the preparation of the Building Block AU, the reaction of 4,N-dimethoxy-3,N-dimethyl-benzamide, beforehand prepared by a standard condensation of 4-methoxy-3-methyl-benzoic acid and N,O-dimethylhydroxylamine hydrochloride, and 1,3-dibromo-5-(2-methoxy-ethyl)-benzene, beforehand reacted with n-butyl lithium, yielded the title compound as a colourless oil (yield: 53% of theory). Mass (calculated) C18H19BrO3 [362]; (found) [M+H]+=363, 365.

Provenance & Evidence