反应详情

The title compound was prepared from 4-chloro-2-methyl-6-nitro-quinazoline (80 mg, 0.36 mmol), 3,4-dimethoxy-aniline (54.8 mg, 0.36 mmol) and sodium acetate (35.2 mg, 0.43 mmol) similar to example 20 to give 109 mg (89.5%) of yellow solids. 1H NMR (CDCl3): 8.87 (d, J=2.7 Hz, 1H), 8.56 (dd, J=2.4 Hz, J=9.0 Hz, 1H), 7.91 (d, J=9.0 Hz, 1H), 7.63-7.61 (m, 2H), 7.28-7.24 (m, 1H), 6.94 (d, J=8.7 Hz, 1H), 3.96 (s, 3H)), 3.93 (s, 3H), 2.71 (s, 3H).