4-Fluorobenzyl bromide → N-(4-fluorobenzyl)-2-(3-(4-fluorobenzyl)-2-oxopyrrolidin-1-yl)-4-methylthiazole-5-carboxamide
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([F:9])[cH:7][cH:8]1.[F:10][c:11]1[cH:12][cH:13][c:14]([CH2:15][NH:16][C:17](=[O:18])[c:19]2[c:20]([CH3:30])[n:21][c:22]([N:24]3[C:25](=[O:29])[CH2:26][CH2:27][CH2:28]3)[s:23]2)[cH:31][cH:32]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([F:9])[cH:7][cH:8]1)[CH:26]1[C:25](=[O:29])[N:24]([c:22]2[n:21][c:20]([CH3:30])[c:19]([C:17]([NH:16][CH2:15][c:14]3[cH:13][cH:12][c:11]([F:10])[cH:32][cH:31]3)=[O:18])[s:23]2)[CH2:28][CH2:27]1Participants
3
Sources & evidence
- ORD record
- ord-b3fbfa2c5f97464db233de76674dcd3d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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