Succinic anhydride → HCID 11293419, compound

Participants

Reaction Steps

A solution of 75 mg of succinic anhydride (0.75 mM) and 250 mg (0.75 mM) of N-ethyl-N′-(6-methyl-5H-pyrido[3′,4′:4,5]pyrrolo[2,3-g]isoquinolin-10-yl)propane-1,3-diamine in 80 ml of dry toluene was brought to reflux for 4 h. The precipitate obtained after cooling was dried and recrystallized with acetone. 240 mg (65.6%) was obtained in the form of solid (F˜150°). Centesimal analysis for C24H27N5O3+3H2O; Calc.: C, 59.12; H, 6.82; N, 14.37; Exp.; C, 59.14; H, 6.88; N, 14.17. NMR and MS in agreement.

Provenance & Evidence