HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1669223Generated: November 5, 2026
3-(4-Benzyloxy-benzoylamino)-propionic acid methyl ester → 3-(4-Hydroxy-benzoylamino)-propionic acid methyl ester
https://huagongshe.com/reaction/1669223
Participants
| Role | Name | HCID | Charge |
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| Reactant | 3-(4-Benzyloxy-benzoylamino)-propionic acid methyl ester | HCID 26635368 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(4-Hydroxy-benzoylamino)-propionic acid methyl ester | HCID 10632853 | — |
Reaction Steps
A mixture of 3-(4-benzyloxy-benzoylamino)-propionic acid methyl ester (11.26 g, 35.93 mmol) and Pd(OH)2/C (20%, 3.19 g) in MeOH was heated at 40° C. for 12 h. The mixture was filtered through celite to yield 7.89 (98%) of the title compound. The following compound was made in a similar manner:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07989457B2 |
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| Source dataset | uspto-grants-2011_08 |
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| ORD ID | ord-4028aead678a4a908c8d9f043528f55b |
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| Source note | uspto-grants-2011_08 |
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