Hydrochloric Acid → HCID 11634204, compound

Participants

Reaction Steps

A solution of ethyl 3-{4-[1-(4′-trifluoromethylbiphenyl-4-yl)propoxy]benzoylamino}propionate (Isomer 2) (90 mg, 0.185 mmol) in THF (1.85 mL) is treated with 5 N NaOH (0.186 mL) and shaken at RT overnight. The reaction is neutralized with 1 N HCl (0.93 mL), and extracted into dichloromethane (3×). The combined organic layers are dried and concentrated, giving the title compound (79 mg). MS (ES): 472.1 [M+H]+.

Provenance & Evidence