HCID 131716375, compound → HCID 136344250, compound

Participants

Reaction Steps

To a mixture of 70 mg of 4-hydroxy-3-[3-[3-[N-(t-butoxycarbonyl)-2-aminoethoxy]phenyl]-1-oxo-2-propenyl]-1,6-dimethyl-2(1H)-pyridinone and 7 ml of chloroform was added 23 μl of trimethylsilane iodide, this was stirred at room temperature for 30 minutes, 46 μl of trimethylsilane iodide was further added, and this was stirred at room temperature for 30 minutes. The solvent was distilled off under reduced pressure, and the resulting crystals were filtered, and washed to obtain 25 mg of 4-hydroxy-3-[3-[3-(2-aminoethoxy)phenyl]-1-oxo-2-propenyl]-1,6-dimethyl-2(1H)-pyridinone [Compound No. (52a)] as a yellow crystal.

Provenance & Evidence