Dimethyl Sulfate → HCID 67345292, compound

HRID 1669375Notes

Reaction equation

[OH:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]([CH3:9])[C:4](=[O:10])[C:3]=1[C:11](=[O:26])[CH:12]=[CH:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH2:21][C:22]([O:24][CH3:25])=[O:23])[CH:15]=1.S(OC)(O[CH3:31])(=O)=O>>[CH3:31][O:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]([CH3:9])[C:4](=[O:10])[C:3]=1[C:11](=[O:26])[CH:12]=[CH:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH2:21][C:22]([O:24][CH3:25])=[O:23])[CH:15]=1

Participants

Reactant 2

HCID 6497Dimethyl Sulfate

HCID 136344252HCID 136344252, compound

Product 1

HCID 67345292HCID 67345292, compound

Procedure

According to the same manner as that of Example a-25 except that 0.71 g of 4-hydroxy-3-[3-[3-(methoxycarbonylmethoxy)phenyl]-1-oxo-2-propenyl]-1,6-dimethyl-2(1H)-pyridinone was used in place of 4-hydroxy-3-[3-[3-(2-hydroxyethoxy)phenyl]-1-oxo-2-propenyl]-1,6-dimethyl-2(1H)-pyridinone, and 0.28 ml of dimethyl sulfate was used in place of iodomethane, 0.37 g of 4-methoxy-3-[3-[3-(methoxycarbonylmethoxy)phenyl]-1-oxo-2-propenyl]-1,6-dimethyl-2(1H)-pyridinone [Compound No. (60a)] was obtained as a pale yellow crystal.

Sources & evidence

ORD record: ord-a7e9157782fb4167a77343b135843fdb
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07989478B2

Reaction notes

Loading…