Ethanol → HCID 136344266, compound

HRID 1669386Notes

Reaction equation

HRID 1669386 reaction equation
[C:1]([C:4]1[C:5](=[O:15])[N:6]([CH2:12][CH:13]=[CH2:14])[C:7]([CH3:11])=[CH:8][C:9]=1[OH:10])(=[O:3])[CH3:2].[CH2:16]([OH:18])[CH3:17]>>[CH2:12]([N:6]1[C:7]([CH3:11])=[CH:8][C:9]([OH:10])=[C:4]([C:1](=[O:3])[CH:2]=[CH:8][C:9]2[CH:4]=[CH:1][CH:2]=[C:16]([O:18][CH2:11][C:7]#[N:6])[CH:17]=2)[C:5]1=[O:15])[CH:13]=[CH2:14]

Participants

3

Reactant 2

HCID 702EthanolHCID 54725053HCID 54725053, compound

Product 1

HCID 136344266HCID 136344266, compound

Procedure

According to the same manner as that of Example a-5 except that 0.20 g of 3-acetyl-1-allyl-4-hydroxy-6-methyl-2(1H)-pyridinone was used in place of 3-acetyl-4-hydroxy-1,6-dimethyl-2(1H)-pyridinone, and 6 ml of ethanol was used in place of pyridine, 0.23 g of 1-allyl-3-[3-[3-(cyanomethoxy)phenyl]-1-oxo-2-propenyl]-4-hydroxy-6-methyl-2(1H)-pyridinone [Compound No. (1c)] was obtained as a yellow crystal.

Sources & evidence

ORD record
ord-e685e0069c95492d8d5e1c1e5bc4f1ed
Source dataset
uspto-grants-2011_08
Patent number
US07989478B2

Reaction notes

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