Trifluoroacetic acid → HCID 67346915, compound

Participants

Reaction Steps

A solution of (7S)-7-[(1-{2-[{[(tert-butoxycarbonyl)amino]sulfonyl}(methyl)amino]ethyl}-pyrrolidin-2-yl)methoxy]-14-cyclohexyl-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (7 mM) in DCM was treated with an excess of TFA (>100 eq). The mixture was stirred at RT for 3.5 h. Volatiles were removed in vacuo. The residue was dissolved in toluene and re-evaporated to drive off excess TFA. The material was taken on without further purification. (ES+) m/z 611 (M+H)+.

Provenance & Evidence