Sodium Hydroxide → 4-azidobutanoic Acid

HRID 1669479Notes

Reaction equation

HRID 1669479 reaction equation
[N:1]([CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8])=[N+:2]=[N-:3].[OH-].[Na+]>CO>[N:1]([CH2:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8])=[N+:2]=[N-:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 13202491Methyl 4-azidobutanoate

Product 1

HCID 118047834-azidobutanoic Acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Methyl 4-azidobutanoate was suspended in 1N NaOH (1.2 eq) and the minimum of MeOH was added to make the reaction mixture homogenous. After 1 h at RT temperature, MeOH was removed in vacuo. The aqueous solution

Workup

  1. customAfter 1 h at RT temperature, MeOH was removed in vacuo

Sources & evidence

ORD record
ord-addf8ec2b522498fb66858206aa8654e
Source dataset
uspto-grants-2011_08
Patent number
US07989438B2

Reaction notes

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