Hydrochloric Acid → HCID 24815793, compound

Participants

Reaction Steps

To the alcohol from step 1 (26 mg) was added 4.0 M HCl in dioxane (0.5 mL). After 3 h, the dioxane was removed to give 22 mg of product. 1H NMR (400 MHz, DMSO-d6) δ 2.57-2.63 (m, 3H), 2.80 (dd, J=13.6, 10.4 Hz, 1H), 3.02 (dd, J=13.6, 4.8 Hz, 1H), 3.23-3.43 (m, 2H), 3.55-3.62 (m, 1H), 5.43 (br s, 1H), 6.96-7.16 (m, 9H), 7.28-7.43 (m, 4H), 8.70 (br s, 1H), 8.91 (br s, 1H); LCMS; 100%, ESI+, Calcd: 349.43 m/z. Found 350.9 (M+1) m/z.

Provenance & Evidence