反应详情

To the 250 ml 3-necked flask was added 10.0 gm 2-ethyl 1-hexanol, 100 ml dichloromethane, and 6.0 gm pyridine and the contents were stirred for 10 minutes. To this mixture, 14.2 gm 4-nitro benzoyl chloride was added slowly and stirred under reflux conditions for 2 hrs. The reaction mixture was then cooled, washed with 20% aqueous ammonium hydroxide. The organic layer was washed with 1N hydrochloric acid and brine, and dried over anhydrous sodium sulfate to give a crude product (˜65% yield).

1. stirringstirred under reflux conditions for 2 hrs
2. temperatureThe reaction mixture was then cooled
3. washwashed with 20% aqueous ammonium hydroxide
4. washThe organic layer was washed with 1N hydrochloric acid and brine
5. dry with materialdried over anhydrous sodium sulfate