Lactide, L- → HCID 131729080, compound

Participants

Reaction Steps

According to the molar ratio of L-Lactide: 3-[4-(benzyloxycarbonylamino) butyl]-morpholine-2,5-dione monomer=1: 49, 44.2 g L-Lactide and 2 g 3-[4-(benzyloxycarbonylamino) butyl]-morpholine-2,5-dione monomer are weighed and put into ampule. Then 5 ml stannous octoate chloroform solution of 30 mg/ml is injected. After volatilization of the chloroform under vacuum, the ampule is sealed with alcohol blast burner. Finally, the sealed ampule is put into oil-bath of 90-140° C. for 12-72 h to obtain poly (glycolic acid-Nε-benzyloxycarbonyl-L-lysine-L-lactic acid).

Provenance & Evidence