(4S)-(4-methyl-2,5-dioxoimidazolidin-4-yl)methanesulphonyl chloride → HCID 86617250, compound

HRID 1669659Notes

Reaction equation

HRID 1669659 reaction equation
[Cl-].[F:2][C:3]([F:15])([F:14])[S:4]([O:7][C:8]1[CH2:9][CH2:10][NH2+:11][CH2:12][CH:13]=1)(=[O:6])=[O:5].[CH3:16][C@@:17]1([CH2:24][S:25](Cl)(=[O:27])=[O:26])[C:21](=[O:22])[NH:20][C:19](=[O:23])[NH:18]1>>[F:15][C:3]([F:2])([F:14])[S:4]([O:7][C:8]1[CH2:13][CH2:12][N:11]([S:25]([CH2:24][C@:17]2([CH3:16])[C:21](=[O:22])[NH:20][C:19](=[O:23])[NH:18]2)(=[O:26])=[O:27])[CH2:10][CH:9]=1)(=[O:6])=[O:5]

Participants

3

Reactant 2

HCID 16738713(4S)-(4-methyl-2,5-dioxoimidazolidin-4-yl)methanesulphonyl chlorideHCID 87365984HCID 87365984, compound

Product 1

HCID 86617250HCID 86617250, compound

Procedure

4-{[(Trifluoromethyl)sulfonyl]oxy}-1,2,3,6-tetrahydropyridinium chloride was reacted with [(4S)-4-methyl-2,5-dioxoimidazolidin-4-yl]methanesulfonyl chloride (Example 1f) in the same way as for Example 1c.

Sources & evidence

ORD record
ord-aaef689f8e4b46bba53634d7b52907e3
Source dataset
uspto-grants-2011_08
Patent number
US07989620B2

Reaction notes

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