2-Chloro-5-nitroquinoline → HCID 44217990, compound

HRID 1669707Notes

Reaction equation

HRID 1669707 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]([F:27])([F:26])[O:17][C:18]1[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=1[CH2:20][NH2:21]>>[F:15][C:16]([F:26])([F:27])[O:17][C:18]1[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=1[CH2:20][NH:21][C:8]1[CH:7]=[CH:6][C:5]2[C:4]([NH2:1])=[CH:13][CH:12]=[CH:11][C:10]=2[N:9]=1

Participants

3

Reactant 2

HCID 3192512-Chloro-5-nitroquinolineHCID 2777251(2-(Trifluoromethoxy)phenyl)methanamine

Product 1

HCID 44217990HCID 44217990, compound

Procedure

The title compound, MS: m/e=334.3 (M+H+), was prepared in accordance with the general method of example 1 from 5-nitro-2-chloroquinoline and 2-(trifluoromethoxy)benzylamine.

Sources & evidence

ORD record
ord-d09c95585d2f4801bf7ba9faa8c05919
Source dataset
uspto-grants-2011_08
Patent number
US07989628B2

Reaction notes

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