2-Chloro-5-nitroquinoline → N2-(2-Methyl-2,3-dihydro-benzofuran-7-yl)-quinoline-2,5-diamine

HRID 1669709Notes

Reaction equation

HRID 1669709 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][CH:16]1[CH2:20][C:19]2[CH:21]=[CH:22][CH:23]=[C:24]([NH2:25])[C:18]=2[O:17]1>>[CH3:15][CH:16]1[CH2:20][C:19]2[CH:21]=[CH:22][CH:23]=[C:24]([NH:25][C:8]3[CH:7]=[CH:6][C:5]4[C:4]([NH2:1])=[CH:13][CH:12]=[CH:11][C:10]=4[N:9]=3)[C:18]=2[O:17]1

Participants

3

Reactant 2

HCID 3192512-Chloro-5-nitroquinolineHCID 13535826HCID 13535826, compound

Product 1

HCID 44217992N2-(2-Methyl-2,3-dihydro-benzofuran-7-yl)-quinoline-2,5-diamine

Procedure

The title compound, MS: m/e=292.0 (M+H+), was prepared in accordance with the general method of example 1 from 5-nitro-2-chloroquinoline and 2,3-dihydro-2-methyl-7-benzofuranamine (CAS 26210-74-2).

Sources & evidence

ORD record
ord-d5ccacedf6fc4a849fc1b0a752b4d757
Source dataset
uspto-grants-2011_08
Patent number
US07989628B2

Reaction notes

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