HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-amine → N2-(2,2-Dimethyl-2,3-dihydro-benzofuran-7-yl)-N5-(1,1-dioxo-hexahydro-1lambda6-thiopyran-4-yl)-quinoline-2,5-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-amine | HCID 91697 | — |
| Reactant | 2H-Thiopyran-4-amine, tetrahydro-, 1,1-dioxide | HCID 418808 | — |
| Reactant | 2-Chloro-5-iodoquinoline | HCID 45789424 | — |
| Product | N2-(2,2-Dimethyl-2,3-dihydro-benzofuran-7-yl)-N5-(1,1-dioxo-hexahydro-1lambda6-thiopyran-4-yl)-quinoline-2,5-diamine | HCID 86634269 | — |
Reaction Steps
The title compound, MS: m/e=438.3 (M+H+), was prepared in accordance with the general method of example 3 from 2-chloro-5-iodo-quinoline (CAS 455955-26-7), 7-amino-2,3-dihydro-2,2-dimethylbenzofuran (CAS 68298-46-4) and 1,1-dioxo-tetrahydro-2H-thiopyran-4-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989628B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-8a45f76229814b008e7b06104aa66888 |
| Source note | uspto-grants-2011_08 |