Propyl 3-aminobut-2-enoate → n-Propyl 5-benzoyl-2,6-dimethyl-4-(2-methyl-4-oxo-4h-chromen-8-yl)-1,4-dihydropyridine-3-carboxylate

Participants

Reaction Steps

250 mg (0.75 mmol) of 2-[(2-methyl-4-oxo-4H-chromen-8-yl)methylene]-1-phenylbutane-1,3-dione are dissolved with 143 mg (1.0 mmol) of n-propyl 3-aminocrotonate in 5 ml of ethanol and heated under reflux under argon for 24 h. The reaction solution is purified by preparative HPLC.

Provenance & Evidence