1-(Pyrazin-2-yl)ethanamine → HCID 57770697, compound

HRID 1669900Notes

Reaction equation

HRID 1669900 reaction equation
[CH:1]([C:4]1[N:8]([C:9]2[CH:10]=[C:11]([C:22](O)=[O:23])[CH:12]=[C:13]([C:15]3[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=3)[CH:14]=2)[C:7]([CH3:25])=[N:6][N:5]=1)([CH3:3])[CH3:2].[N:26]1[CH:31]=[CH:30][N:29]=[CH:28][C:27]=1[CH:32]([NH2:34])[CH3:33]>>[N:26]1[CH:31]=[CH:30][N:29]=[CH:28][C:27]=1[CH:32]([NH:34][C:22]([C:11]1[CH:12]=[C:13]([C:15]2[CH:16]=[CH:17][C:18]([CH3:21])=[CH:19][CH:20]=2)[CH:14]=[C:9]([N:8]2[C:7]([CH3:25])=[N:6][N:5]=[C:4]2[CH:1]([CH3:3])[CH3:2])[CH:10]=1)=[O:23])[CH3:33]

Participants

3

Reactant 2

HCID 185190061-(Pyrazin-2-yl)ethanamineHCID 57770709HCID 57770709, compound

Product 1

HCID 57770697HCID 57770697, compound

Procedure

5-(3-Isopropyl-5-methyl-[1,2,4]triazol-4-yl)-4′-methyl-biphenyl-3-carboxylic acid (1-pyrazin-2-yl-ethyl)-amide was prepared from 5-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-4′-methyl-biphenyl-3-carboxylic acid and 1-pyrazin-2-yl-ethylamine using the procedure of step 4 of Example 6.

Sources & evidence

ORD record
ord-c94d95cbbc5c4893b4cb5b026e99f8bc
Source dataset
uspto-grants-2011_08
Patent number
US07989637B2

Reaction notes

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