2,4-Difluorophenol → HCID 11990507, compound

HRID 1669974Notes

Reaction equation

HRID 1669974 reaction equation
C[O:2][C:3](=[O:20])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=[O:19])[C:12]1[CH:17]=[CH:16][C:15](I)=[CH:14][CH:13]=1.[F:21][C:22]1[CH:27]=[C:26]([F:28])[CH:25]=[CH:24][C:23]=1[OH:29]>>[F:21][C:22]1[CH:27]=[C:26]([F:28])[CH:25]=[CH:24][C:23]=1[O:29][C:15]1[CH:16]=[CH:17][C:12]([C:11]([NH:10][C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([OH:2])=[O:20])=[O:19])=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 1230512,4-DifluorophenolHCID 1019269HCID 1019269, compound

Product 1

HCID 11990507HCID 11990507, compound

Procedure

In analogy to example 2,-[4-(2,4-Difluoro-phenoxy)-benzoylamino]-benzoic acid was prepared from 2-(4-iodo-benzoylamino)-benzoic acid methyl ester [75541-84-3] and 2,4-difluoro-phenol. MS (m/e): 367.1 (M−H−, 100%).

Sources & evidence

ORD record
ord-2a35806227444e629b0754d7183769c3
Source dataset
uspto-grants-2011_08
Patent number
US07989657B2

Reaction notes

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