HCID 67345904, compound → HCID 67344911, compound

HRID 1670011Notes

Reaction equation

HRID 1670011 reaction equation
C(N(N1CCCC1)C1C=CC(F)=CC=1F)(=O)C(C)C.C([N:30]1[CH2:34][CH2:33][C@H:32]([N:35]([C:43](=[O:52])[C:44]([CH3:51])([CH3:50])[CH2:45][O:46][C:47](=[O:49])[CH3:48])[CH:36]2[CH2:41][CH2:40][CH:39]([F:42])[CH2:38][CH2:37]2)[CH2:31]1)(OCC1C=CC=CC=1)=O>>[C:47]([O:46][CH2:45][C:44]([CH3:51])([CH3:50])[C:43]([N:35]([CH:36]1[CH2:37][CH2:38][CH:39]([F:42])[CH2:40][CH2:41]1)[C@H:32]1[CH2:33][CH2:34][NH:30][CH2:31]1)=[O:52])(=[O:49])[CH3:48]

Participants

3

Reactant 2

HCID 67345904HCID 67345904, compound2×HCID 86612821HCID 86612821, compound

Product 1

HCID 67344911HCID 67344911, compound

Procedure

The title compound was prepared following the procedure described in Intermediate 64 using the product of Step B, (3S)-1-cbz-3-[acetyloxypivaloyl(4-fluoro-cyclohexyl)amino]pyrrolidine.

Sources & evidence

ORD record
ord-df043890fb024760bcea95a52c4de0e1
Source dataset
uspto-grants-2011_08
Patent number
US07989634B2

Reaction notes

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