反应详情

A mixed solution of 4.1 g of pyrene, 2 g of tert-butyl chloride and 33 ml of dichloromethane was cooled to 0° C. under a nitrogen stream, and 2.7 g of aluminum chloride was added thereto. After the mixed solution was stirred at room temperature for 3 hours, 30 ml of water was added thereto, and the mixture was extracted with 30 ml of dichloromethane. The organic layer was washed twice with 20 ml of water, dried over magnesium sulfate and then evaporated. The resulting residue was purified by silica gel column chromatography and dried under vacuum to give 3 g of 2-tert-butylpyrene (65% content).

1. additionwas added
2. extractionthe mixture was extracted with 30 ml of dichloromethane
3. washThe organic layer was washed twice with 20 ml of water
4. dry with materialdried over magnesium sulfate
5. customevaporated
6. customThe resulting residue was purified by silica gel column chromatography
7. customdried under vacuum