反应详情

3-Benzo[1,3]dioxol-5-yl-5-benzyloxy-benzoic acid methyl ester (14.2 g) was dissolved in 1,4-dioxane (200 mL) and then 1 M aq. NaOH (40 mL) was added. The mixture was stirred at room temperature overnight. The solvents were removed under reduced pressure and the residue was diluted with water (200 mL). It was then made acidic by addition of 10% HCl (aq.) solution and the precipitated material was collected by filtration. The solid was washed with water and dried to yield 13.2 g (97% yield) of the title compound.

1. customThe solvents were removed under reduced pressure
2. additionthe residue was diluted with water (200 mL)
3. additionmade acidic by addition of 10% HCl (aq.) solution
4. filtrationthe precipitated material was collected by filtration
5. washThe solid was washed with water
6. customdried