5-{6-[2-(2-Ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-3'-fluoro-biphenyl-3-carboxylic acid tert-butyl ester → HCID 67338241, compound

HRID 1670085Notes

Reaction equation

HRID 1670085 reaction equation
[C:1]([O:5][C:6]([C:8]1[CH:9]=[C:10]([C:43]2[CH:48]=[CH:47][CH:46]=[C:45](F)[CH:44]=2)[CH:11]=[C:12]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([O:27][CH2:28][CH2:29][CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32])[C:22]=2[CH2:36][CH2:37][C:38]([O:40][CH2:41][CH3:42])=[O:39])[CH:13]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C([O:54][C:55](=[O:72])C1C=C(O)C=C(C2C=CC3OCOC=3C=2)C=1)(C)(C)C>>[C:1]([O:5][C:6](=[O:7])[C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([O:27][CH2:28][CH2:29][CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32])[C:22]=2[CH2:36][CH2:37][C:38]([O:40][CH2:41][CH3:42])=[O:39])[CH:11]=[C:10]([C:43]2[CH:48]=[CH:47][C:46]3[O:54][CH2:55][O:72][C:45]=3[CH:44]=2)[CH:9]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Procedure

The title compound was prepared in the same way as 5-{6-[2-(2-ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-3′-fluoro-biphenyl-3-carboxylic acid tert-butyl ester starting from 3-benzo[1,3]dioxol-5-yl-5-hydroxy-benzoic acid tert-butyl ester.

Sources & evidence

ORD record
ord-f119689c517d4c7a94821a78cb50e31c
Source dataset
uspto-grants-2011_08
Patent number
US07989454B2

Reaction notes

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