HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylhomopiperazine → 4-(2-(2-Carboxy-ethyl)-3-{6-[3'-fluoro-5-(4-methyl-[1,4]diazepane-1-carbonyl)-biphenyl-3-yloxy]-hexyl}-phenoxy)-butyric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylhomopiperazine | HCID 228349 | — |
| Reactant | HCID 67338077 | HCID 67338077 | — |
| Product | 4-(2-(2-Carboxy-ethyl)-3-{6-[3'-fluoro-5-(4-methyl-[1,4]diazepane-1-carbonyl)-biphenyl-3-yloxy]-hexyl}-phenoxy)-butyric Acid | HCID 67338056 | — |
Reaction Steps
The title compound was prepared according to the general procedure described in Steps 7 and 8 of Method C starting from 5-{6-[2-(2-ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-3′-fluoro-biphenyl-3-carboxylic acid and 1-methyl-[1,4]diazepane (15% yield after two steps).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989454B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-12b4304d6b9f405b8c73addfed601f7a |
| Source note | uspto-grants-2011_08 |