Cyclopropylamine → 4-(2-(2-Carboxy-ethyl)-3-{6-[3-cyclopropylcarbamoyl-5-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenoxy]-hexyl}-phenoxy)-butyric Acid

Participants

Role	Name	HCID	Charge
Reactant	Cyclopropylamine	HCID 69828	—
Reactant	3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-5-{6-[2-(2-ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-benzoic Acid	HCID 67338007	—
Product	4-(2-(2-Carboxy-ethyl)-3-{6-[3-cyclopropylcarbamoyl-5-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenoxy]-hexyl}-phenoxy)-butyric Acid	HCID 67338034	—

Reaction Steps

The title compound was prepared according to the general procedure described in Example 74 starting from 3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-{6-[2-(2-ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-benzoic acid and cyclopropylamine.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07989454B2
Source dataset	uspto-grants-2011_08
ORD ID	ord-27d8a2eae865452daa0d15c38862a283
Source note	uspto-grants-2011_08