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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1670108Generated: October 30, 2026

Dimethylamine → 4-(2-(2-Carboxy-ethyl)-3-{6-[3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-dimethylcarbamoyl-phenoxy]-hexyl}-phenoxy)-butyric Acid

https://huagongshe.com/reaction/1670108

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-5-{6-[2-(2-ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-benzoic AcidHCID 67338007—
Product4-(2-(2-Carboxy-ethyl)-3-{6-[3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-dimethylcarbamoyl-phenoxy]-hexyl}-phenoxy)-butyric AcidHCID 67339816—

Reaction Steps

The title compound was prepared according to the general procedure described in Example 74 starting from 3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-{6-[2-(2-ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-benzoic acid and dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989454B2
Source datasetuspto-grants-2011_08
ORD IDord-a0ffddb1cdae4589ac59ab5ed1df07b2
Source noteuspto-grants-2011_08