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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1670109Generated: October 29, 2026

p-Fluorophenethylamine → 4-[2-(2-Carboxy-ethyl)-3-(6-{3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-[2-(4-fluoro-phenyl)-ethylcarbamoyl]-phenoxy}-hexyl)-phenoxy]-butyric Acid

https://huagongshe.com/reaction/1670109

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-FluorophenethylamineHCID 4653—
Reactant3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-5-{6-[2-(2-ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-benzoic AcidHCID 67338007—
Product4-[2-(2-Carboxy-ethyl)-3-(6-{3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-[2-(4-fluoro-phenyl)-ethylcarbamoyl]-phenoxy}-hexyl)-phenoxy]-butyric AcidHCID 67339013—

Reaction Steps

The title compound was prepared according to the general procedure described in Example 74 starting from 3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-{6-[2-(2-ethoxycarbonyl-ethyl)-3-(3-ethoxycarbonyl-propoxy)-phenyl]-hexyloxy}-benzoic acid and 2-(4-fluoro-phenyl)-ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989454B2
Source datasetuspto-grants-2011_08
ORD IDord-5fca24f3c72c4d8ba9b0d17c40c47cbb
Source noteuspto-grants-2011_08