HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-3-nitrobenzamide → 2,3-Diaminobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-3-nitrobenzamide | HCID 10797476 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2,3-Diaminobenzamide | HCID 10487029 | — |
Reaction Steps
The mixture of 206 g (1.14 mol) of 6 and 20.6 g of 10% Pd on charcoal in 824 ml of THF and 824 ml of methanol was hydrogenated with a total of 6 equivalents of hydrogen (130 l) at 2048° C. over 24 h. The mixture was filtrated and the solvents were evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07994160B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-2033a63806ac4af69be48e9b150f8549 |
| Source note | uspto-grants-2011_08 |