Sodium 2-ethylhexanoate → HCID 57617740, compound

Participants

Reaction Steps

181 mg of 2 (742 μmol), 180 mg of 20 (742 μmol) and 296 mg of sodium 2-ethylhexanoate (1.78 mmol) in 3 mL of THF are successively introduced into a 25 mL round-bottomed flask, with stirring and under an argon atmosphere. The stirring is maintained at RT for 24 h. The mixture is concentrated and 727 mg of crude product are obtained, which product is chromatographed on a silica cartridge [50 g, eluent heptane/AcOEt-heptanel (50/50), in an AcOEt-heptane (50/50) gradient: 0 to 100%]. 177 mg of expected product Ex9 are recovered.

Provenance & Evidence