Succinic Acid → HCID 67336831, compound

Participants

Reaction Steps

To a solution of 7-chloro-6-(4,5-dihydro-thiazol-2-ylthiomethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine (0.57 g, 1.8 mmol) in absolute ethanol (10 mL), add succinic acid (0.217 g, 1.83 mmol). After acid dissolves, concentrate the reaction mixture in vacuo. Combine the residue with MTBE, concentrate in vacuo several times and dry under high vacuum at room temperature overnight to obtain the title compound (0.79 g, 100%) as a white foam. MS (ES+) m/z/z: 313.0 (M+H)+.

Provenance & Evidence