Methanol → 3-fluoro-4-(2-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)benzenamine
Reaction equation
[BH4-:34].[CH3:36][OH:37].[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12](-[c:14]2[n:15][cH:16][n:17]([CH2:19][O:20][CH2:21][CH2:22][Si:23]([CH3:24])([CH3:25])[CH3:26])[cH:18]2)[s:13]3)[cH:27][cH:28][c:29]([N+:31]([O-:32])=[O:33])[cH:30]1.[Na+:35].[Ni:38]([Cl:39])[Cl:40]>>[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12](-[c:14]2[n:15][cH:16][n:17]([CH2:19][O:20][CH2:21][CH2:22][Si:23]([CH3:24])([CH3:25])[CH3:26])[cH:18]2)[s:13]3)[cH:27][cH:28][c:29]([NH2:31])[cH:30]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-13efa0bc27e241338761b9094f105b59
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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