Hydrogen Bromide → HCID 67340484, compound

Participants

Reaction Steps

A suspension of 9-methoxy-1-methyl-6-(4-nitrophenyl)-pyrido[2′,1′:2,3]imidazo-[4,5-c]isoquinolin-5(6H)-one (I30) (0.14 mmol, 0.056 g) in a concentrated aqueous HBr solution (5 ml) was refluxed overnight. The reaction mixture was concentrated under reduced pressure. The crude product was brought on a filter and washed with isopropanol and isopropylether to give the hydrobromide salt of 9-hydroxy-1-methyl-6-(4-nitrophenyl)-pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5(6H)-one (110) (0.010 g, yield=17%, purity (LC)=91%).

Provenance & Evidence