1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → HCID 11960469, compound

Participants

Reaction Steps

To a solution of the product of step b (20 mg) in 2 mL of dichloromethane were added EDCI (7.0 mg), DIPEA (7 μL) and 2-thiophenemethylamine (4.1 μL) and the reaction mixture was stirred for 3 h. at room temperature. The reaction mixture was concentrated and the title compound was obtained after flash column chromatography (silica gel, heptane/ethyl acetate (1/4, v/v), Rf=0.78).

Provenance & Evidence