N-bromobutanimide → Methyl 2-bromo-2-(4-chlorophenyl)acetate

HRID 1670853Notes

Reaction equation

HRID 1670853 reaction equation
[CH3:1][O:2][C:3](=[O:12])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][CH:6]=1.C1C(=O)N([Br:20])C(=O)C1>C(Cl)(Cl)(Cl)Cl>[CH3:1][O:2][C:3](=[O:12])[CH:4]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][CH:6]=1)[Br:20]

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 104196Methyl 4-chlorophenylacetate

Product 1

HCID 10777987Methyl 2-bromo-2-(4-chlorophenyl)acetate

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

2-Bromo-(p-chlorophenyl)-acetic acid methyl ester was prepared from (4-chlorophenyl)-acetic acid methyl ester (2.5 g, 13.5 mmol) and NBS (2.52 g, 14.1 mmol) in CCl4.

Sources & evidence

ORD record
ord-b76fd7f855bb4629a8af4c6cf8727023
Source dataset
uspto-grants-2011_08
Patent number
US07994172B2

Reaction notes

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