1-Amino-2-cyclopropylpropan-2-ol → N-(2-cyclopropyl-2-hydroxypropyl)-7,7-dimethyl-6,8-dihydro-5H-quinoline-2-carboxamide
Reaction equation
[CH3:1][C:2]1([CH3:15])[CH2:3][CH2:4][c:5]2[cH:6][cH:7][c:8]([C:12](=[O:13])[OH:14])[n:9][c:10]2[CH2:11]1.[NH2:16][CH2:17][C:18]([OH:19])([CH:20]1[CH2:21][CH2:22]1)[CH3:23]>>[CH3:1][C:2]1([CH3:15])[CH2:3][CH2:4][c:5]2[cH:6][cH:7][c:8]([C:12](=[O:14])[NH:16][CH2:17][C:18]([OH:19])([CH:20]3[CH2:21][CH2:22]3)[CH3:23])[n:9][c:10]2[CH2:11]1Participants
3
Sources & evidence
- ORD record
- ord-9d8916463b6743cc9957b9d6ab949a98
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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