Hydroxide → 2-[3-Chloro-5-[[1-(cyclopropylmethyl)piperidin-2-yl]methylamino]-2-methyl-6-oxopyrazin-1-yl]acetic acid

HRID 167117Notes

Reaction equation

HRID 167117 reaction equation
[Cl:1][c:2]1[c:3]([CH3:32])[n:4]([CH2:21][C:22](=[O:23])[O:24][CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:5](=[O:20])[c:6]([NH:8][CH2:9][CH:10]2[N:11]([CH2:16][CH:17]3[CH2:18][CH2:19]3)[CH2:12][CH2:13][CH2:14][CH2:15]2)[n:7]1.[OH-:33].[OH-:35].[Pd+2:34]>>[Cl:1][c:2]1[c:3]([CH3:32])[n:4]([CH2:21][C:22](=[O:23])[OH:24])[c:5](=[O:20])[c:6]([NH:8][CH2:9][CH:10]2[N:11]([CH2:16][CH:17]3[CH2:18][CH2:19]3)[CH2:12][CH2:13][CH2:14][CH2:15]2)[n:7]1

Participants

4

Reactant 3

HCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 59900602HCID 59900602, compound

Product 1

HCID 599005582-[3-Chloro-5-[[1-(cyclopropylmethyl)piperidin-2-yl]methylamino]-2-methyl-6-oxopyrazin-1-yl]acetic acid

Sources & evidence

ORD record
ord-4f14b925b5634fed943d2304eb027535
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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