5-Bromo-2-methoxy-4-methylpyridine → 2-Bromo-1-(2,6-dimethoxy-pyridin-3-yl)-propan-1-one

HRID 1671323Notes

Reaction equation

HRID 1671323 reaction equation
[Br:1][CH:2]([CH3:14])[C:3]([C:5]1[CH:6]=[N:7][C:8]([O:12][CH3:13])=[CH:9][C:10]=1C)=[O:4].BrC1C(C)=C[C:19]([O:22]C)=NC=1>>[Br:1][CH:2]([CH3:14])[C:3]([C:5]1[C:6]([O:22][CH3:19])=[N:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=1)=[O:4]

Participants

3

Reactant 2

HCID 41780025-Bromo-2-methoxy-4-methylpyridineHCID 591860502-Bromo-1-(6-methoxy-4-methyl-pyridin-3-yl)-propan-1-one

Product 1

HCID 866389392-Bromo-1-(2,6-dimethoxy-pyridin-3-yl)-propan-1-one

Procedure

This compound is prepared analogously to 2-bromo-1-(6-methoxy-4-methyl-pyridin-3-yl)-propan-1-one (Intermediate DA) by replacing 5-bromo-2-methoxy-4-methyl-pyridine with the appropriate starting compound. MS: m/z 274 [M+H]+

Sources & evidence

ORD record
ord-ec443db547b648deba83199fd2abc679
Source dataset
uspto-grants-2011_08
Patent number
US07994203B2

Reaction notes

Loading…