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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1671357Generated: October 25, 2026

2-Bromo-1-(4-bromo-2-methylphenyl)propan-1-one → 2-Bromo-1-(2-chloro-4-[1,2,4]triazol-1-yl-phenyl)-butan-1-one

https://huagongshe.com/reaction/1671357

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-(4-bromo-2-methylphenyl)propan-1-oneHCID 18520183—
Reactant2-Chloro-4-(1H-1,2,4-triazol-1-yl)-benzenecarboxylic acidHCID 18795027—
ReactantHCID 178418443HCID 178418443—
Product2-Bromo-1-(2-chloro-4-[1,2,4]triazol-1-yl-phenyl)-butan-1-oneHCID 86638942—

Reaction Steps

This compound is prepared from 2-chloro-4-[1,2,4]triazol-1-yl-benzoic acid analgously to 2-bromo-1-(4-bromo-2-methyl-phenyl)-propan-1-one (Intermediate MA) by replacing ethylmagnesium bromide with the appropriate alkyl magnesium bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07994203B2
Source datasetuspto-grants-2011_08
ORD IDord-6ab47deff1b24250acf9d92a02d111fe
Source noteuspto-grants-2011_08