1-(2-Methoxy-4-methylphenyl)propan-1-one → 1-(5-Chloro-3-methyl-2-phenyl-3H-imidazol-4-yl)-propan-1-one

HRID 1671360Notes

Reaction equation

HRID 1671360 reaction equation
[Cl:1][C:2]1[N:6]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:4]([CH3:13])[C:3]=1[CH:14]=[O:15].CO[C:18]1C=C(C)C=C[C:19]=1C(=O)CC>>[Cl:1][C:2]1[N:6]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:4]([CH3:13])[C:3]=1[C:14](=[O:15])[CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 42837091-(2-Methoxy-4-methylphenyl)propan-1-oneHCID 866380455-Chloro-3-methyl-2-phenyl-3H-imidazole-4-carbaldehyde

Product 1

HCID 673369451-(5-Chloro-3-methyl-2-phenyl-3H-imidazol-4-yl)-propan-1-one

Procedure

The title compound is prepared from 5-chloro-3-methyl-2-phenyl-3H-imidazole-4-carbaldehyde analogously to 1-(2-methoxy-4-methyl-phenyl)-propan-1-one (Intermediate N).

Sources & evidence

ORD record
ord-124c294676224a3c9e21de4fa2cec608
Source dataset
uspto-grants-2011_08
Patent number
US07994203B2

Reaction notes

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