Sodium Azide → HCID 131729102, compound

Participants

Reaction Steps

Following the general procedure for the preparation of azides of Description 16, 2-morpholin-4-ylethyl (2R/S)-4-[(3-chloropropyl)sulfonyloxy]-2-[(4-methoxyphenyl)methoxy]-3,3-dimethylbutanoate (27a) (0.22 g, 0.42 mmol) dissolved in 5 mL of anhydrous dimethyl sulfoxide (DMSO) was reacted with 68 mg (1.0 mmol) of sodium azide (NaN3). After work-up, the crude material (27b) was used in the next step without further purification. MS (ESI) m/z 523.07 (M+H)+.

Provenance & Evidence