Sodium Azide → HCID 86629047, compound

Participants

Reaction Steps

Following the general procedure for the preparation of azides of Description 16, (1S)-1-phenylethyl (2R)-4-[(3-chloropropyl)sulfonyloxy]-2-hydroxy-3,3-dimethylbutanoate (35b) (0.30 g, 0.76 mmol) dissolved in 6 mL of anhydrous dimethyl sulfoxide (DMSO) was reacted with 99 mg (1.53 mmol) of sodium azide (NaN3). After work-up, the crude material (35c) was used in the next step without further purification. MS (ESI) m/z 422.05 (M+Na)+.

Provenance & Evidence