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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1671517Generated: November 1, 2026

Ethanolamine → 3-[3-(2-Fluoro-benzoylamino)-phenoxymethyl]-thieno[3,2-c]pyridine-7-carboxylic acid (2-hydroxy-ethyl)-amide

https://huagongshe.com/reaction/1671517

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
Reactant3-[3-(2-Fluoro-benzoylamino)-phenoxymethyl]-thieno[3,2-c]pyridine-7-carboxylic acid ethyl esterHCID 24800267—
Product3-[3-(2-Fluoro-benzoylamino)-phenoxymethyl]-thieno[3,2-c]pyridine-7-carboxylic acid (2-hydroxy-ethyl)-amideHCID 24800442—

Reaction Steps

3-[3-(2-Fluoro-benzoylamino)-phenoxymethyl]-thieno[3,2-c]pyridine-7-carboxylic acid (2-hydroxy-ethyl)-amide was prepared from 3-[3-(2-fluoro-benzoylamino)-phenoxymethyl]-thieno[3,2-c]pyridine-7-carboxylic acid ethyl ester (from Example 12 supra) and ethanolamine (Aldrich) following the procedure described in Example 16 as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07994321B2
Source datasetuspto-grants-2011_08
ORD IDord-25a9f00a9b624b3d9898079eccbad17b
Source noteuspto-grants-2011_08